High Resolution Oxygen Measurements

Needle-Type Oxygen Microsensor NTH-PSt7

The glass fiber with its oxygen-sensitive tip (< 50 µm with tapered sensor tip TS, < 230 µm with flat-broken sensor tip TF) is protected inside a stainless steel needle and can be extended for measurements. As long as the sensor tip is retracted and sheltered inside this needle the microsensor can be pierced through septum rubber or any other harsh material. With its small tip size and fast response time (t90 < 3 s) this sensor is ideally suited for research and packaging applications, where micro-invasive and small sensors are needed.

  • High spatial resolution (down to < 50 μm)
  • High temporal resolution (t90 < 3 sec.)
  • No consumption of oxygen
  • Signal independent of flow velocity
  • Measures in liquids as well as in gas phase


Tissue Engineering

Oxygen microsensors measure the oxygen content in various volume compartments of the tissue engineering constructs. To do so, hair-thin sensors are inserted into the constructs and the oxygen content is measured online. In this way, the oxygen partial pressure is measured with a high local resolution and correlated with the constructs tissue quality (composition of the extracellular matrix).

Packaging & Quality Control

Oxygen inside packaging can lead to oxidative deterioration of certain products. Therefore, determination of the oxygen content within packages or pharmaceutical vials is of essential importance to ensure both the filling quality and the long-term storage stability. With our micro-invasive needle-type oxygen microsensors we offer a simple tool to determine residual oxygen both in the headspace and in liquids. The septum of the vial or package is pierced with the needle and the sensor is extended for measurement. As the measurement is made inside the package no error-prone and time consuming sampling is necessary. These oxygen microsensors are ideal tools for quality control in the food & beverage, packaging, and pharmaceutical industries.


Specifications*Gaseous & Dissolved O2Dissolve O2
*data for microsensor TF = flat-broken sensor tip with 230 μm diameter
Measurement range0 – 100 % O2
0 – 1000 hPa

0 – 45 mg/L

0 – 1400 µmol/L
Limit of detection0.03 % oxygen15 ppb

± 0.01 % O2 at 1  % O2
± 0.05 % O2 at 20.9 % O2

± 0.005 mg/L at  0.4mg/L

± 0.025 mg/L at 9.06 mg/L
Accuracy at + 20 °C± 0.05 % O2 or ± 3 % rel.
Measurement temperature rangefrom 0 to + 50 °C
Response time (t90)< 3 sec. (gas)< 10 sec. (liquid)
CompatibilityAqueous solutions, ethanol, methanol
No cross-sensitivity

pH 1 – 14
CO2, H2S, SO2
Ionic species


Organic solvents, such as acetone, toluene, chloroform or methylene chloride
Chlorine gas

Sterilization procedure

Ethylene oxide (EtO)

Cleaning procedure

3 % H2O2
Soap solution

CalibrationTwo-point calibration with oxygen-free environment (nitrogen, sodium sulfite) and air-saturated environment
Storage stability24 months provided the sensor material is stored in the dark at room temperature

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