CO2 Measurement in Microfluidic Devices

Christopher Long, Wesley Anderson, Craig Finch, and James Hickman

GEN Vol. 32 No.18, 2012

Facilitating Biological Applications Using a Flow-Through Cell

The reliable, noninvasive measurement of dissolved gases in microfluidic devices in an important and difficult activity for biological applications. The PreSens pCO2 mini and chemical optical CO2 sensors have been designed to noninvasively measure carbon dioxide in the recirculating fluid in these devices. The small CO2 sensor spot placed in contact with the solution takes up a small volume and has a thin profile, at approximately 5 mm diameter and 0.1 mm thickness. Microfluidic devices for biological applications limit the culture media to small volumes and small flow rates, creating the advantage of minimizing the use of reagents.


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