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Seeing Metabolic Activity

February 16, 2011

2D sensing of oxygen distribution by combining digital imaging technology with optical sensor technology will be presented by PreSens Precision Sensing at SMI Imaging in Cancer Drug Development in London.

Due to the innovative imaging system by PreSens typical samples as tissues (animal or plant), cell suspensions, sediments or similar complex biological solutions or gels can be analysed two-dimensionally. Especially heterogeneous tissue samples can now easily be evaluated with respect to structural and suspicious changes (cancer). This is possible as one single image contains the information of an array of single point sensors - this leads to the cartography of metabolic activity. Given the 2D sensing of oxygen distribution, it will be much easier to determine the effects of cancer treatment on the local growth of the carcinoma.

The system itself consists of a camera-equipped detection head, a control and evaluation software and a typically 2.5 x 2 cm flexible sensor foil with a spatial resolution of ˜ 100 µm - shaped to any desired geometry just using scissors - which is sensitive against O2. The customized software allows controlling the image recording process and assists image processing and evaluation. An easy to use camera controlling user interface manages image acquisition and storage. Measurements which belong together can be organized as user defined sessions in separate folders and annotated with a free text comment.

About PreSens Precision Sensing GmbH

PreSens Precision Sensing GmbH is a leading developer, manufacturer and distributor of chemical optical sensors. Its continuously expanding range of sensor systems for O2, pH and CO2 is for end users in Biotech & Pharma, Food & Beverage, Scientific Applications and OEM manufacturers for Medical Devices. Founded as a spin-off from the University of Regensburg /Bavaria back in 1997, PreSens has evolved to be an organization dedicated to bring together state-of-the-art sensor technology and customer needs. The more than 50 employees and a network of contract developers and suppliers from the heart of German engineering are the company´s most important resource: Maintaining flexibility while developing and manufacturing according to highest qualtity standards as ISO 9001:2008 and ISO 13485:2003. This is the challenge they master every day. From its site in Regensburg, Germany, PreSens offers full service in Europe, America and Asia - together with its distributors and partners.

Contact:

Christina Schlauderer
Communications
PreSens Precision Sensing GmbH
Phone: +49 941 94 27 21 09
E-Mail: christina.schlauderer@presens.de


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