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Find Publications and Information about Your Optical Sensor System
Whether it is general information or detailed, application based data on optical sensors you are looking for, in our collection of publications, sensor basics and FAQs you will find what you need. Furthermore, short tutorial videos and our instruction manuals will help you with handling your sensor system.
Why It Is Important to Measure Different Parameters Online in Shake Flasks: SFR vario Measures O2, OUR, pH and Biomass Online
R. W. Maschke1, G. T. John2, and D. Eibl1
1 ZHAW Zurich University of Applied Sciences, School of Life Sciences and Facility Management, Wädenswil, Switzerland
2PreSens Precision Sensing GmbH, Regensburg, Germany
Optical sensors enable monitoring and controlling important culture parameters even at shake flask scale. In this short report we show an example of multiparameter monitoring with…
Download PDFO2, pH and CO2 Monitoring in Microfluidic Mammalian Cell Culture: Cultivated Meat Bioprocess Optimization with SensorPlugs
Vasa Radonic, Ivana Podunavac, Mila Djisalov, Teodora Knezic, Ivana Gadjanski
BioSense Institute, Novi Sad, Serbia
We tested the efficacy of PreSens SensorPlugs for monitoring mammalian cell culturing processes in microfluidic bioreactors (MBs) with integrated sensors. MRC-5 fibroblasts (ATCC®…
Download PDFCultivated Meat Bioprocess Optimization: O2, pH and CO2 Monitoring in E. coli Culture with PreSens SensorPlugs
Vasa Radonic, Ivana Podunavac, Mila Djisalov, Teodora Knezic, Ivana Gadjanski
BioSense Institute, Novi Sad, Serbia
We tested the efficacy of PreSens SensorPlugs for monitoring bacterial cultures in microfluidic bioreactors (MBs), which is important in the context of monitoring potential…
Download PDFOnline CO2 Monitoring in CHO Cell Culture: Bypass-pCO2 Measurements
Christoph Neubrand, Johannes Wirth, Dietmar Lang, Marvin Kadisch, Konstantin Bagnjuk
Rentschler Biopharma SE, Laupheim, Germany
A fed-batch-process with Horizon’s glutamine synthetase knockout CHO cell line was carried out in an autoclavable 10L benchtop bioreactor. For online culture monitoring PreSens’…
Download PDFEvaluation of an Optical CO2 Probe for Long-Term Monitoring in Stirred-Tank Bioreactors: Prototype Autoclavable CO2 Sensor Used in Low and High Cell Density Cultures
Melissa Hill1, Marcelo Kern1, Sayantan Bose1, Athanas Apostolidis2
1GlaxoSmithKline, King of Prussia, PA, USA
2PreSens Precision Sensing GmbH, Regensburg, Germany
When culturing mammalian cells, carbon dioxide gas is an important factor to stabilize the pH in the medium and to adjust the atmosphere to physiological levels for the respective…
Download PDFDirect Measurements of pCO2 in the Digestive Tract of Fish: Use of fiber optic pCO2 microsensors to reliably measure in vivo pCO2 in various sections of the gastrointestinal system in several fish species
Chris M. Wood1,2, Junho Eom1,2, Ellen H. Jung1,2, and Fernando Martinez Ferreras3
1Department of Zoology, University of British Columbia, Vancouver, B. C., Canada
2Bamfield Marine Sciences Centre, Bamfield, B. C., Canada
3PreSens Precision Sensing GmbH, Regensburg, Germany
Our objective was to measure the pCO2 levels in the fluids of the stomach and various sections of the intestine in both fasted and fed fish, weighing typically 50 - 300 g. It was…
Download PDFMonitoring in an Isolated Perfused Heart Test Stand with PreSens Optical Sensors: O2, CO2 and Glucose Flow-through Cells Integrated in a Blood Perfusion System
Daniela Obermaier1 & Giuliano Giacoppo2
1PreSens Precision Sensing GmbH, Regensburg, Germany
2Regensburg Center of Biomedical Engineering, University of Applied Sciences, Regensburg, Germany
During long-term application of artificial lungs (Extra Corporeal Membrane Oxygenation - ECMO) different complications, like blood clotting, cell destruction (hemolysis), or…
Download PDFIn vivo Monitoring of Haemolymph pCO2 in Dragonfly Nymphs to Determine the Resting State Value: Use of fiber optic pCO2 Microsensors to reliably measure in vivo haemolymph pCO2 in insects
Daniel J. Lee1, Fernando Martinez Ferreras2, Martin Gutbrod2 and Philip G. D. Matthews1
1University of British Columbia, Department of Zoology, British Columbia, Canada
2PreSens Precision Sensing GmbH, Regensburg, Germany
The objective of this study was to monitor the haemolymph pCO2 of water-breathing dragonfly nymphs in vivo. However, the small body size and haemolymph volume of these animals…
Download PDFO2, pH and CO2 Dynamics in Salt Marsh Tidal Ponds: Investigations under Different Light Regimes with Optical Profiling Microsensors and an Automated Micromanipulator
Ketil Koop-Jakobsen1 and Martin Gutbrod2
1University of Bremen, MARUM - Center for Marine Environmental Scienes, Bremen, Germany
2PreSens Precision Sensing GmbH, Regensburg, Germany
Salt marsh ponds are extreme environments characterized by high microbial activity and strong biogeochemical gradients at the sediment water interface. In this study, we…
Download PDFCO2, Oxygen and Biomass Monitoring in E. coli Shake Flask Culture: Following Glucose-Glycerin Diauxie Online with the SFR vario
Helga Tietgens1, Gernot T. John2 and Katja Bettenbrock1
1Max Planck Institut für Dynamik komplexer technischer Systeme, Magdeburg, Germany
2PreSens Precision Sensing GmbH, Regensburg, Germany
Diauxic growth of E. coli in medium containing glycerin and glucose was monitored online with the SFR vario. The device measures biomass online via scattered light detection.…
Download PDFSimultaneous pH, CO2 and O2 Measurements in Algae Photobioreactor: pH Flow-Through Cells successfully evaluated for later use in the International Space Station ISS
Gisela Detrell and Jochen Keppler
Institute of Space Systems, University of Stuttgart, Germany
At the Institute of Space Systems several experiments with algae photobioreactors were conducted, in order to design a system to be tested in the International Space Station in…
Download PDFExchange of O2 and CO2 in the Capillary Fringe of a Porous Medium: A laboratory study testing the VisiSens imaging systems
Christina Haberer1, Massimo Rolle1,2, and Peter Grathwohl1
1Department of Geosciences, University of Tübingen, Germany
2Department of Civil and Environmental Engineering, Stanford University, USA
Diffusion experiments were performed in a quartz sand packing to study the effect of evaporative conditions on mass transfer of oxygen and CO2 across the interface between the…
Download PDFImaging Rhizosphere pH and CO2 Dynamics: Plant Root - Soil Interactions Quantified with Prototype VisiSens Systems
S. Blossfeld1, C. M. Schreiber2, G. Liebsch3, A. J. Kuhn1, and P. Hinsinger2
1Forschungszentrum Jülich GmbH, Institute of Bio- and Geosciences, IBG-2: Plant sciences, Jülich, Germany
2INRA, UMR Eco&Sol, Montpellier, France
3PreSens Precision Sensing GmbH, Regensburg, Germany
Prototype VisiSens™ devices for pH & CO2 imaging were used to perform continuous and highly resolved measurements in rhizobox systems. pH was measured around durum wheat roots…
Download PDFImmobilized Plant Cells - From DSMZ to the Customer: VisiSens technology used to detect metabolic activities of immobilized plant cells during simulated cell transport in a closed system
Nicole Brinkmann, Martina Westphal, Elke Heine-Dobbernack, and Martin Schumacher
Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany
The DSMZ is one of the largest biological resource centers worldwide. Its collections currently comprise almost 40,000 items, including about 700 undifferentiated plant cell lines.…
Download PDFBiogenic Gas Bubbles Produced within Soil Macropores: Simultaneous measurement of gas bubble size and CO2 concentration with VisiSens A3
Yuhong He, Cameron Proctor, and Alex Tong
Department of Geography and Planning, University of Toronto, Canada
Greenhouse gas measurements in wetlands note considerable spatial and temporal variability in biogenic gas bubbles, suggesting microscale heterogeneities influence formation and…
Download PDFO2, CO2 and pH Dynamics in the Capillary Fringe: VisiSens combined with an automated linear positioning system provides complete analyte maps
M. Wagner, N. Hack, G. Abbt-Braun, and H. Horn
Chair of Water Chemistry and Water Technology, Engler-Bunte-Institut, Karlsruhe Institute of Technology, Germany
We investigated the biochemical transformation potential in the capillary fringe (CF) by measuring the distribution of dissolved gases and the pH value. Therefore, we combined the…
Download PDFImpact of dCO2 on Process Parameters: Effect of High dCO2 on Viable Cell Density and Product Titer in CHO Cell Culture
Jennifer Couture, Jennifer Lindsay, and Rick Baggio
EMD Millipore Corporation, Bedford, MA, USA
Real-time monitoring of bioprocess parameters is important to ensure reproducible cell culture and optimize product quality. Fast detection of unfavorable conditions in cell…
Download PDFOnline in Situ Measurements of Soil CO2 Concentrations in Dependence of Ash Roots (Fraxinus excelsior L.)
Ann-Catrin Fender, Christoph Flucke, Dirk Gansert
Department of Plant Ecology and Ecosystem Research, University of Göttingen, Germany
Root-induced temporal and spatial changes of CO2 concentration are of high importance for biogeochemistry of soils, and thus, for their potential of long-term carbon storage. We…
Download PDFMeasuring Dissolved Carbon Dioxide in Microfluidic Devices for Biological Application Using a Flow-Through Cell
Christopher Long, Wesley Anderson, Craig Finch, and James Hickman
Nano Science Technology Center, University of Central Florida, Orlando, FL, USA
The reliable, non-invasive measurement of dissolved gases in microfluidic devices is an important and difficult aspect for biological applications. The PreSens pCO2 mini and…
Download PDFNon-invasive Online CO2 Measurement with Chemical Optical CO2 Sensors: Chemical optical CO2 sensors provide a versatile tool for online monitoring of dissolved CO2 in various scale and designs
Athanas Apostolidis
PreSens Precision Sensing GmbH, 93053 Regensburg, Germany
Accurate CO2 measurement in the liquid phase has been a challenge for decades. Although off-gas measurement by means of IR-spectroscopy is a proven technology, the correlation of…
Download PDFAdvanced Respirometry with Chemical Optical Sensor Spots: Non-invasive Tracking of Oxygen, Carbon Dioxide and pH as Indicator for Nitrification Activity
Eva M. Gilbert, Susanne Lackner
Karlsruhe Institute of Technology (KIT), Engler-Bunte Institute, Water-Chemistry and Water Technology, Karlsruhe, Germany
Respirometry is an indirect way of measuring microbial activity, such as nitrification. The oxygen uptake is proportional to the substrate consumption - given by the stoichiometry…
Download PDFIn situ monitoring reveals cellular environmental instabilities in human pluripotent stem cell culture
Shannon G. Klein, Samhan M. Alsolami, Silvia Arossa, Gerardo Ramos-Mandujano, Anieka J. Parry, Alexandra Steckbauer, Carlos M. Duarte, Mo Li
Communications Biology (2022) 5:119
Online Monitoring of Crude Oil Biodegradation at Elevated Pressures
Ana Gabriela Valladares Juárez, Hari Spandana Kadimesetty, Daniela E. Achatz, Martina Schedler, and Rudolf Müller
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing (2015) Vol. 8, No. 2, 872 - 878