Watch tutorials, webinars and informative videos about PreSens optical sensor systems.
Find Publications and Information about Your Optical Sensor System
Whether it is general information or detailed, application based data on optical sensors you are looking for, in our collection of publications, sensor basics and FAQs you will find what you need. Furthermore, short tutorial videos and our instruction manuals will help you with handling your sensor system.
Monitoring Spatio-Temporal Oxygen Consumption Within Live 3D Cancer Spheroids: VisiSens TD with MIC Kit Enables New Insights
Carina Schmittlein1, Robert Johannes Meier2, Christina Hupf1, Joachim Wegener1,3
1 Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, Regensburg, Germany
2 PreSens Precision Sensing GmbH, Regensburg, Germany
3 Fraunhofer Research Institution for Microsystems and Solid State Technologies (EMFT),
Regensburg, Germany
Testing Plant Seed Viability by Respiration Measurements: Oxygen Consumption Monitoring in 96 Well Plate with VisiSens TD and ViviPlate a Newly Developed Airtight Plate Clamp System
G. Liebsch & R. Meier
PreSens Precision Sensing GmbH, Regensburg, Germany
PreSens has developed the sensor and clamp tool ViviPlate that allows to create closed respirator chambers of different numbers and volumes in microtiterplate format. These…
Download PDFSpatio-temporal O2 Gradients in the Microenvironment of an Outgrowing Cell Patch: Oxygen Imaging in Micro-Scale with the VisiSens TD MIC System
C. Schmittlein1, R. J. Meier2, J. Wegener1,3
1Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, Regensburg, Germany
2PreSens Precision Sensing GmbH, Regensburg, Germany
3Fraunhofer Research Institution for Microsystems and Solid State Technologies (EMFT), Regensburg, Germany
Cell-based assays have emerged to an indispensable tool in all areas of the biomedical sciences. However, cell culture experiments in a laboratory environment are always questioned…
Download PDFNon-invasive pH Monitoring in Anaerobic Clostridium Culture: Evaluation of the pH Sensor Spot SP-LG1 in Low pH Range
Nikola Naschitzki
Beuth University of Applied Sciences, Berlin, Germany
A prototype pH sensor spot type LG1 was integrated in a closed, gas-tight culture bottle for monitoring an anaerobic cultivation of Clostridium acetobutylicum. The sensor allowed…
Download PDFHigh Resolution O2 Microprofiling of a Freshwater Stream Biofilm: Use of an Automated Micromanipulator System and O2 Microsensors in a Flume Experiment
Christine Anlanger1,2, Ute Risse-Buhl1, Kaan Koca1,2, Christian Noss2, Andreas Lorke2, Markus Weitere1, Martin S. Gutbrod3
1Department River Ecology, Helmholtz Centre for Environmental Research - UFZ, Magdeburg, Germany
2Institute for Environmental Sciences, Environmental Physics, University of Koblenz-Landau, Landau, Germany
3PreSens Precision Sensing GmbH, Regensburg, Germany
The objective of this study was to determine oxygen fluxes and the spatial micro-heterogeneity of microbial respiration and photosynthesis of a stream biofilm from the Selke…
Download PDFImproving Culture Conditions of Antibody-Producing Yeast: Use of Deep Well SensorDishes® for pH and DO Monitoring
Lotta Kirjavainen and Alexander Frey
Aalto University, Finland
Reliable screening set-ups are the key to rapid identification of genetic modifications or changes of cultivation conditions improving strain performance. Moreover, online…
Download PDFO2, pH and CO2 Dynamics in Salt Marsh Tidal Ponds: Investigations under Different Light Regimes with Optical Profiling Microsensors and an Automated Micromanipulator
Ketil Koop-Jakobsen1 and Martin Gutbrod2
1University of Bremen, MARUM - Center for Marine Environmental Scienes, Bremen, Germany
2PreSens Precision Sensing GmbH, Regensburg, Germany
Salt marsh ponds are extreme environments characterized by high microbial activity and strong biogeochemical gradients at the sediment water interface. In this study, we…
Download PDFThe Application of the SFR Shake Flask Reader in Teaching at the Esslingen University of Applied Sciences: Non-invasive Measurements of Dissolved Oxygen and pH in Shake Flasks within the Framework of Practical Courses and Student Projects
A. Komitakis, K. Schatz, M. Hoß, R. Biener
Department Biotechnology, Esslingen University of Applied Sciences, Germany
Dissolved oxygen (DO) and pH are key parameters for microbial fermentations and cell cultures. The importance of DO and pH for bioprocesses as well as methods for their measurement…
Download PDFOxygen Gradients in Collagen-I Gels: Automated micromanipulator with fiber optic profiling oxygen microsensor as a method to evaluate oxygen gradients in collagen-I gels for tissue engineering
Laura Heimann1, Paul Wolff1, Elizabeth Rosado Balmayor1, Martijn van Griensven1, Gregor Liebsch2, Robert Meier2, Martin Gutbrod2
1Experimental Trauma Surgery, Technical University of Munich (TUM), Munich, Germany
2PreSens GmbH, Regensburg, Germany
Adipose-derived mesenchymal stem cell loaded collagen-I gels were evaluated with the automated profiling system by PreSens (Automated Micromanipulator AM and Profiling O2…
Download PDFpH Monitoring of Urine and Tumor Microenvironments in Rats: High Spatial Resolution Measurements Controlled with the Manual Micromanipulator
T. Kiskova1, Z. Steffekova2, M. Karasova2, N. Kokosova1
1P. J. Šafárik University in Košice, Faculty of Sciences, Košice, Slovakia
2University of Veterinary Medicine and Pharmacy in Košice, Slovakia
The aim of our study was to monitor pH of urine samples (< 100 µL) and of tumor microenvironments of anesthetized rats in a minimal invasive way. The small urine volumes of rats or…
Download PDFDevelopment of a New, Highly Sensitive Sensor for Permeation Measurement: Optical Sensors Used for Permeation Testing of High Barrier Materials
Christian Huber3, Sven Sängerlaub1, and Kajetan Müller2
1TU Munich, Chair of Food Packaging Technology, Freising, Germany
2Fraunhofer Institute for Process Engineering and Packaging, Freising, Germany
3PreSens Precision Sensing GmbH, Regensburg, Germany
A new measurement system for testing synthetic materials on oxygen permeability was developed. Unlike the currently used systems with electrochemical or barometrical sensors it was…
Download PDFFeedback Controlled Carbon Feeding at Shake Flask Scale: Online measurement of DO with chemical optical sensors by PreSens
Manuela Senn and Martin Ischebeck
DSM Nutritional Products GmbH, Grenzach-Whylen, Germany
In this study a feedback controlled scale-down model at shake flask scale has been developed. Dissolved oxygen (DO) concentration in cultures of Saccharomyces cerevisiae was…
Download PDFCell Growth and Recombinant Protein Production in Small-Scale Culture Vessels: Optical oxygen sensor spots help optimizing culture conditions
V. Jäger1, G. Apati1,2, and N. Konisch1
1Recombinant Gen Expression Group, Helmholtz Centre for Infection Research, Braunschweig, Germany
2Universidade da Região de Joinville, Brazil
Optical measurement of oxygen allows the introduction of small sensor spots into the culture vessels. As many of the conventional sub-bioreactor scale culture vessels are not…
Download PDFOnline pH and DO Measurements in Microcarrier-Based hMSC Cultivations: Culture monitoring with sensor spots integrated in single-use spinner flasks
V. Jossen1, C. Schirmaier1, G. T. John2, D. Eibl1, and R. Eibl1
1Zurich University of Applied Sciences, School of Life Sciences and Facility Management, Institute of Biotechnology, Wädenswil, Switzerland
2PreSens Precision Sensing GmbH, Regensburg, Germany
Spinner flasks are often used for microcarrier-based cultivations of human mesenchymal stem cells (hMSCs). Normally, they are not equipped with pH and dissolved oxygen (DO) probes.…
Download PDFEarly pH Changes in Musculoskeletal Tissues upon Injury - Aerobic Catabolic Pathway Acitvity Linked to Inter-Individual Differences in Local pH
Julia C. Berkmann, Aaron X. Herrera Martin, Agnes Ellinghaus, Claudia Schlundt, Hanna Schell, Evi Lippens, Georg N. Duda, Serafeim Tsitsilonis and Katharina Schmidt-Bleek
Int. J. Mol. Sci. (2020), 21, 2513
The choroid plexus sodium-biocarbonate cotransporter NBCe2 regulates mouse cerebrospinal fluid pH
H. L. Christensen, D. Barbuskaite, A. Rojek, H. Malte, I. B. Christensen, A. C. Füchtbauer, E.-M. Füchtbauer, T. Wang, J. Praetorius, H. H. Damkier
J Physiol 596.19 (2018) 4709-4728
Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status
L. Bramasole, A. Sinha, S. Gurevich, M. Radzinski, Y. Klein, N. Panat, E. Gefen, T. Rinaldi, D. Jimenez-Morales, J. Johnson, N. J. Krogan, N. Reis, D. Reichmann, M. H. Glickman, E. Pick
Redox Biology (2019) 20, 533 - 543
Influence of oxygen deficiency and the role of specific amino acids in cryopreservation of garlic shoot tips
Karthikeyan Subbarayan, Hardy Rolletschek Angelika Senula, Kamatchi Ulagappan, Mohammad-Reza Hajirezaei, and E.R. Joachim Keller
BMC Biotechnology (2015) 15:40